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Voltar para Controle Epigenético da Expressão Gênica

Comentários e feedback de alunos de Controle Epigenético da Expressão Gênica da instituição Universidade de Melbourne

745 classificações

Sobre o curso

While the human genome sequence has transformed our understanding of human biology, it isn’t just the sequence of your DNA that matters, but also how you use it! How are some genes activated and others are silenced? How is this controlled? The answer is epigenetics. Epigenetics has been a hot topic for research over the past decade as it has become clear that aberrant epigenetic control contributes to disease (particularly to cancer). Epigenetic alterations are heritable through cell division, and in some instances are able to behave similarly to mutations in terms of their stability. Importantly, unlike genetic mutations, epigenetic modifications are reversible and therefore have the potential to be manipulated therapeutically. It has also become clear in recent years that epigenetic modifications are sensitive to the environment (for example diet), which has sparked a large amount of public debate and research. This course will give an introduction to the fundamentals of epigenetic control. We will examine epigenetic phenomena that are manifestations of epigenetic control in several organisms, with a focus on mammals. We will examine the interplay between epigenetic control and the environment and finally the role of aberrant epigenetic control in disease. All necessary information will be covered in the lectures, and recommended and required readings will be provided. There are no additional required texts for this course. For those interested, additional information can be obtained in the following textbook. Epigenetics. Allis, Jenuwein, Reinberg and Caparros. Cold Spring Harbour Laboratory Press. ISBN-13: 978-0879697242 | Edition: 1 The course will re-open in 2022....

Melhores avaliações


1 de out de 2018

This was an excellent course. All the material was well presented and the explanation of the sometimes complex subject matter was clear and understandable. Thank you for an great learning experience.


1 de ago de 2021

This is the best course on coursera, 10/10. I wish it was longer and I could take it all over again. you will need background knowledge for this course but it is an amazing course and I will miss it.

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1 — 25 de 204 Avaliações para o Controle Epigenético da Expressão Gênica


20 de mai de 2020

por Ho Y C

10 de mai de 2020


24 de jul de 2019

por Niusha

1 de ago de 2021

por Apoorva S

21 de jul de 2019


23 de mai de 2020

por Udit G

28 de nov de 2020

por Ismael V M

24 de jul de 2019

por Gaurav S

7 de mar de 2017

por Saurabh M

29 de jun de 2017

por Rodrigo A M F

2 de nov de 2016

por Hennecke D

25 de nov de 2019

por robert t

22 de mar de 2016

por Dong M

31 de jul de 2017

por Didi-Morgan

30 de ago de 2018

por Christie S

9 de ago de 2019

por Talha I

16 de mai de 2019

por Camilo G

1 de dez de 2020

por Mostafa E

28 de ago de 2017

por Felipe C D S B

30 de nov de 2020

por Arturo M

28 de ago de 2017

por Dr L S N

18 de mai de 2020

por Miguel L E

18 de jul de 2016

por Beatric S

12 de nov de 2020

por C. R

21 de ago de 2016