Informações sobre o curso
4.8
161 classificações
34 avaliações
Programa de cursos integrados
100% online

100% online

Comece imediatamente e aprenda em seu próprio cronograma.
Prazos flexíveis

Prazos flexíveis

Redefinir os prazos de acordo com sua programação.
Nível iniciante

Nível iniciante

Horas para completar

Aprox. 15 horas para completar

Sugerido: 3 hours/week...
Idiomas disponíveis

Inglês

Legendas: Inglês, Chinês (simplificado)

Habilidades que você terá

AlgorithmsPython ProgrammingWhole Genome SequencingDynamic Programming
Programa de cursos integrados
100% online

100% online

Comece imediatamente e aprenda em seu próprio cronograma.
Prazos flexíveis

Prazos flexíveis

Redefinir os prazos de acordo com sua programação.
Nível iniciante

Nível iniciante

Horas para completar

Aprox. 15 horas para completar

Sugerido: 3 hours/week...
Idiomas disponíveis

Inglês

Legendas: Inglês, Chinês (simplificado)

Programa - O que você aprenderá com este curso

Semana
1
Horas para completar
4 horas para concluir

Week 1: Introduction to Genome Sequencing

<p>Welcome to class!</p><p>This course will focus on two questions at the forefront of modern computational biology, along with the algorithmic approaches we will use to solve them in parentheses:</p><ol><li>Weeks 1-2: How Do We Assemble Genomes? (<i>Graph Algorithms</i>)</li><li>How Do We Sequence Antibiotics? (<i>Brute Force Algorithms</i>)</li></ol><p>Each of the two chapters of content in the class is accompanied by a Bioinformatics Cartoon created by talented San Diego artist Randall Christopher and serving as a chapter header in the Specialization's bestselling <a href="http://bioinformaticsalgorithms.com" target="_blank">print companion</a>. You can find the first chapter's cartoon at the bottom of this message. What does a time machine trip to 1735, a stack of newspapers, a jigsaw puzzle, and a giant ant invading a riverside city have to do with putting together a genome? Start learning today to find out!</p><p><img src="https://d396qusza40orc.cloudfront.net/bioinformatics%2Fimages%2Fchapter4_final_lr.jpg" title="Image: https://d396qusza40orc.cloudfront.net/bioinformatics%2Fimages%2Fchapter4_final_lr.jpg" width="528"></p>...
Reading
8 videos (Total 36 min), 2 leituras, 3 testes
Video8 videos
FIELD TRIP!4min
What Is Genome Sequencing?6min
Exploding Newspapers4min
The String Reconstruction Problem3min
String Reconstruction as a Hamiltonian Path Problem3min
String Reconstruction as an Eulerian Path Problem5min
Similar Problems with Different Fates 3min
Reading2 leituras
Course Details10min
Week 1 FAQs (Optional)0
Quiz1 exercício prático
Week 1 Quiz15min
Semana
2
Horas para completar
3 horas para concluir

Week 2: Applying Euler's Theorem to Assemble Genomes

<p>Welcome to Week 2 of class!</p> <p>This week in class, we will see how a 300 year-old mathematical theorem will help us assemble a genome from millions of tiny pieces of DNA.</p>...
Reading
5 videos (Total 28 min), 1 leitura, 3 testes
Video5 videos
Euler's Theorem 6min
Assembling Read-Pairs 8min
De Bruijn Graphs Face Harsh Realities of Assembly 4min
Returning to Konigsberg 1min
Reading1 leituras
Week 2 FAQs (Optional)0
Quiz1 exercício prático
Week 2 Quiz15min
Semana
3
Horas para completar
4 horas para concluir

Week 3: Sequencing Antibiotics

<p>Welcome to Week 3 of class!</p> <p>This week, we begin a new chapter, titled "How Do We Sequence Antibiotics?" &nbsp;In this chapter, we will learn&nbsp;how to determine the amino acid sequences making up antibiotics using brute force algorithms.</p> <p>Below is this week's Bioinformatics Cartoon.</p> <p><img src="https://d396qusza40orc.cloudfront.net/bioinformatics%2Fimages%2Fchapter2_final.jpg" title="Image: https://d396qusza40orc.cloudfront.net/bioinformatics%2Fimages%2Fchapter2_final.jpg" width="528"></p>...
Reading
5 videos (Total 27 min), 1 leitura, 3 testes
Video5 videos
How Do Bacteria Make Antibiotics? 8min
Sequencing Antibiotics by Shattering Them into Pieces 4min
A Brute Force Algorithm for Cyclopeptide Sequencing 3min
Cyclopeptide Sequencing with Branch and Bound 6min
Reading1 leituras
Week 3 FAQs (Optional)0
Quiz1 exercício prático
Week 3 Quiz15min
Semana
4
Horas para completar
3 horas para concluir

Week 4: From Ideal to Real Spectra for Antibiotics Sequencing

<p>Welcome to Week 4 of class!</p> <p>Last week, we discussed how to sequence an antibiotic peptide from an ideal spectrum. This week, we will see how to develop more sophisticated algorithms for antibiotic peptide sequencing that are able to handle spectra with many false and missing masses.</p>...
Reading
4 videos (Total 18 min), 1 leitura, 3 testes
Video4 videos
From 20 to More than 100 Amino Acids 2min
The Spectral Convolution Saves the Day 6min
The Truth About Spectra 2min
Reading1 leituras
Week 4 FAQs (Optional)0
Quiz1 exercício prático
Week 4 Quiz15min
4.8
34 avaliaçõesChevron Right
Direcionamento de carreira

50%

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Benefício de carreira

83%

consegui um benefício significativo de carreira com este curso

Melhores avaliações

por SVJan 10th 2017

Great course to explore a bit of Bioinformatics for those with no background in Bioinformatics. I love the way the content has been provided, its interactivity increases the interest in the course.

por MPDec 8th 2017

I like the real-world tasks, especially the assembly on the final exam. Some of the programming tasks, such as the antibiotic noisy spectrum assembly, are challenging (which is good).

Instrutores

Avatar

Pavel Pevzner

Professor
Department of Computer Science and Engineering
Avatar

Phillip Compeau

Visiting Researcher
Department of Computer Science & Engineering

Sobre University of California San Diego

UC San Diego is an academic powerhouse and economic engine, recognized as one of the top 10 public universities by U.S. News and World Report. Innovation is central to who we are and what we do. Here, students learn that knowledge isn't just acquired in the classroom—life is their laboratory....

Sobre o Programa de cursos integrados Bioinformatics

Join Us in a Top 50 MOOC of All Time! How do we sequence and compare genomes? How do we identify the genetic basis for disease? How do we construct an evolutionary Tree of Life for all species on Earth? When you complete this Specialization, you will learn how to answer many questions in modern biology that have become inseparable from the computational approaches used to solve them. You will also obtain a toolkit of existing software resources built on these computational approaches and that are used by thousands of biologists every day in one of the fastest growing fields in science. Although this Specialization centers on computational topics, you do not need to know how to program in order to complete it. If you are interested in programming, we feature an "Honors Track" (called "hacker track" in previous runs of the course). The Honors Track allows you to implement the bioinformatics algorithms that you will encounter along the way in dozens of automatically graded coding challenges. By completing the Honors Track, you will be a bioinformatics software professional! Learn more about the Bioinformatics Specialization (including why we are wearing these crazy outfits) by watching our introductory video. You can purchase the Specialization's print companion, Bioinformatics Algorithms: An Active Learning Approach, from the textbook website. Our first course, "Finding Hidden Messages in DNA", was named a top-50 MOOC of all time by Class Central!...
Bioinformatics

Perguntas Frequentes – FAQ

  • Ao se inscrever para um Certificado, você terá acesso a todos os vídeos, testes e tarefas de programação (se aplicável). Tarefas avaliadas pelos colegas apenas podem ser enviadas e avaliadas após o início da sessão. Caso escolha explorar o curso sem adquiri-lo, talvez você não consiga acessar certas tarefas.

  • Quando você se inscreve no curso, tem acesso a todos os cursos na Especialização e pode obter um certificado quando concluir o trabalho. Seu Certificado eletrônico será adicionado à sua página de Participações e você poderá imprimi-lo ou adicioná-lo ao seu perfil no LinkedIn. Se quiser apenas ler e assistir o conteúdo do curso, você poderá frequentá-lo como ouvinte sem custo.

Mais dúvidas? Visite o Central de Ajuda ao Aprendiz.