This course familiarizes students with the novel concepts being used to revamp regulatory toxicology in response to a breakthrough National Research Council Report “Toxicity Testing in the 21st Century: A Vision and a Strategy.” We present the latest developments in the field of toxicology—the shift from animal testing toward human relevant, high content, high-throughput integrative testing strategies. Active programs from EPA, NIH, and the global scientific community illustrate the dynamics of safety sciences.
oferecido por
Toxicology 21: Scientific Applications
Universidade Johns HopkinsInformações sobre o curso
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Prazos flexíveis
Redefinir os prazos de acordo com sua programação.
Certificados compartilháveis
Tenha o certificado após a conclusão
100% on-line
Comece imediatamente e aprenda em seu próprio cronograma.
Nível intermediário
Aprox. 96 horas para completar
Inglês
Legendas: Francês, Portuguese (European), Russo, Inglês, Espanhol
Prazos flexíveis
Redefinir os prazos de acordo com sua programação.
Certificados compartilháveis
Tenha o certificado após a conclusão
100% on-line
Comece imediatamente e aprenda em seu próprio cronograma.
Nível intermediário
Aprox. 96 horas para completar
Inglês
Legendas: Francês, Portuguese (European), Russo, Inglês, Espanhol
oferecido por
Universidade Johns Hopkins
The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world.
Programa - O que você aprenderá com este curso
75 horas para concluir
Module 1
This model will give you a broad introduction to the Toxicology 21st century (Tox21c) field and familiarize you with the main document, which summarize the main ideas and principles of Tox21c.
75 horas para concluir
10 vídeos (Total 121 mín.), 3 leituras, 1 teste
4 horas para concluir
Module 2
This module will discuss how ToxCast and Tox21 technologies can be used in practice. The US EPA Endocrine Disruptor Screening Program will be discussed in detail and we will demonstrate how the ToxCast platform replaced in vivo tiered approaches in EDSP and, thus, acelerate the process of . In the second lesson of this module, the development of in silico models for toxicity testing will be discussed.
4 horas para concluir
10 vídeos (Total 119 mín.), 4 leituras, 2 testes
3 horas para concluir
Module 3
This module will familiarize you with the Human Toxome Project run by Johns Hopkins University in collaboration with several university, industry, and research agencies. Omics technologies, their advantages and disadvantages, as well as concepts of Adverse Outcome Pathways (AOP) and Pathways of Toxicity (PoT) will be discussed.
3 horas para concluir
11 vídeos (Total 126 mín.), 2 leituras, 1 teste
4 horas para concluir
Module 4
The first lesson in this module will explain the concept of read-across, why it is important for regulatory risk assessment, and how it can be implemented by industry in response to REACH legislation. The organotypic cultures lesson will teach you about existing in vitro cell-based models starting from simple monolayer cultures of cell lines and ending with complex combined organ-on-a-chip and human-on-a-chip approaches.
4 horas para concluir
15 vídeos (Total 148 mín.), 3 leituras, 2 testes
2 horas para concluir
Module 5
This module will teach you the role of miRNA and epigenetics in toxicology and environmental health.
2 horas para concluir
6 vídeos (Total 41 mín.), 1 leitura, 1 teste
Avaliações
Principais avaliações do TOXICOLOGY 21: SCIENTIFIC APPLICATIONS
por I25 de Mai de 2020
one of the best course helps students & researcher about what are challenges faced in toxicology in 21 century and finds the routes to develop new routes and methods for toxicology tests
por S3 de Mai de 2018
Very nicely designed course. The instructors offer an excellent and easy to understand overview of a range of promising Tox21 tools and approaches using good examples and illustrations.
por MM29 de Nov de 2020
Very nice and the teachers explanation are clear . It’s very interesting, specially if you work in the research-lab section
por NK26 de Dez de 2018
A very well-taught course with lots of useful information. I highly recommend it.
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