Informações sobre o curso
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Nível iniciante

Aprox. 15 horas para completar

Sugerido: 7 weeks of study, 2-4 hours per week...

Inglês

Legendas: Inglês

100% online

Comece imediatamente e aprenda em seu próprio cronograma.

Prazos flexíveis

Redefinir os prazos de acordo com sua programação.

Nível iniciante

Aprox. 15 horas para completar

Sugerido: 7 weeks of study, 2-4 hours per week...

Inglês

Legendas: Inglês

Programa - O que você aprenderá com este curso

Semana
1
2 horas para concluir

Introduction & Shortcomings of Current Approaches

This module introduces you to the course, outlines the shortcomings of current toxicity testing approaches, and shows how EBT can help to overcome these shortcomings....
9 vídeos (total de (Total 66 mín.) min), 3 leituras, 1 teste
9 videos
Introduction to the Course14min
Introduction5min
Shortcoming No. 1: Narrative Reviews7min
Shortcoming No. 2: Bias in Reviews7min
Shortcoming No. 3: Evidence Writing4min
Shortcoming No. 4: External Validity10min
Shortcoming No. 5: Assessing New Methods5min
Shortcoming No. 6: Inadequate Reporting7min
3 leituras
Letter to Learners10min
Course Learning Objectives10min
Supporting reading10min
1 exercício prático
Practice Quiz 18min
Semana
2
3 horas para concluir

History and Causation

This module explains how evidence-based toxicology originated and describes the driving forces for the initiative. In the second lesson, you will learn how to distinguish between correlation and causation as well as the main problems with drawing conclusions on the basis of correlations. The Bradford Hill criteria are introduced, along with examples for each criterion. You will also learn about mechanistic toxicology and mechanistic validation....
11 vídeos (total de (Total 138 mín.) min), 2 leituras, 1 teste
11 videos
Personal First Exposures to Evidence-Based Medicine21min
The Start of EBT16min
The First Conference 2007 to the Start of the EBT Collaboration 201114min
The Evidence-Based Toxicology Collaboration (EBTC)13min
Introduction Causation vs. Correlation18min
The Hill Principles of Epidemiology and their Relation to Toxicology16min
The Problem of Causation in Toxicology16min
Biomarker Concept in Mechanistic Toxicology4min
Mechanistic Validation4min
The Future of Causation in Complex Systems9min
2 leituras
Supporting reading10min
Supporting reading10min
1 exercício prático
Practice Quiz 210min
Semana
3
3 horas para concluir

Systematic Review and Meta-Analysis

This module shows how to perform systematic reviews and meta-analyses. You will learn the history of both methods and will receive step-by-step instructions on how to perform systematic reviews and meta-analyses using examples from the research activities of the instructors. ...
8 vídeos (total de (Total 101 mín.) min), 2 leituras, 2 testes
8 videos
Systematic Reviews: Definition and Principles26min
Systematic Reviews - Protocol Development15min
Systematic Reviews - Protocol Development (Part 2)19min
History5min
Meta-analysis Guidelines7min
Meta-analysis Protocol, Part 110min
Meta-analysis Protocol, Part 212min
2 leituras
Supporting reading10min
Supporting reading10min
2 exercícios práticos
Practice Quiz 36min
Mid-course exam30min
Semana
4
2 horas para concluir

Risk of Bias & Application to Test Methods Comparison

This module teaches you about possible biases that can be introduced at different stages of research. Each bias is explained with examples, including solutions for overcoming those biases. The second lesson covers systematic review of the zebrafish embryotoxicity test as a case study conducted by the Evidence-based Toxicology Collaboration (EBTC). You will go through all of the steps of the systematic review again to imprint the knowledge from module 3, but this systematic review will be related to a toxicological method....
8 vídeos (total de (Total 94 mín.) min), 2 leituras, 1 teste
8 videos
Introduction to Risk of Bias Concept in Critical Appraisal of Studies26min
Examples for Risk of Bias Tools 1: Cochrane Collboration4min
Examples for Risk of Bias Tools 2: SYRCLE's RoB Tool5min
Examples of Risk of Bias Tools 3: National Institute for Environmental Health Sciences (NIEHS) - OHAT12min
Quality Assessment in Evidence-Based Toxicology7min
Evidence-Based Toxicology (EBT) and Evidence-Based Toxicology Collaboration (EBTC)11min
Zebrafish Systematic Review22min
2 leituras
Supporting reading10min
Supporting reading10min
1 exercício prático
Practice Quiz 410min
4.8
1 avaliaçõesChevron Right

Melhores avaliações

por EEApr 6th 2019

Surprisingly very informative and detailed Course. Thanks for the load of information given.

Instrutores

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Thomas Hartung

Professor
Environmental Health and Engineering
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Lena Smirnova

Research Associate
Center for Alternatives to Animal Testing

Sobre Universidade Johns Hopkins

The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world....

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