Informações sobre o curso
4.8
179 classificações
37 avaliações

100% online

Comece imediatamente e aprenda em seu próprio cronograma.

Prazos flexíveis

Redefinir os prazos de acordo com sua programação.

Aprox. 14 horas para completar

Sugerido: 2-4 hours/week...

Inglês

Legendas: Inglês

100% online

Comece imediatamente e aprenda em seu próprio cronograma.

Prazos flexíveis

Redefinir os prazos de acordo com sua programação.

Aprox. 14 horas para completar

Sugerido: 2-4 hours/week...

Inglês

Legendas: Inglês

Programa - O que você aprenderá com este curso

Semana
1
3 horas para concluir

UNIT 1: INTRODUCTION TO PERSONALIZED MEDICINE

The first module of this course will focus on introducing the concept of personalized medicine. We will very briefly review fundamentals of genetics as these apply to personalized medicine (DNA structure; RNA; protein structures; function of DNA; coding; DNA variations; types of genetic variants), as well as review statistical concepts and skills important to clinical data analysis (odds ratios, relative risk, P values, multiple testing, sensitivity, specificity, ROCs). In Module 2 we will explore drug actions and reactions as we look closely at the general mechanisms underlying variability in drug responses, drug metabolism and transport, and genetic variability in drug-handling molecules....
11 vídeos (total de (Total 120 mín.) min), 1 leitura, 1 teste
11 videos
Introduction to Personalized Medicine11min
Genetics Definitions, Part I14min
Genetics Definitions, Part II & Types of Genetic Variants15min
Data Analysis, Part I: What is a Good Study?12min
Data Analysis, Part II: What is a Good Test?7min
Introduction to Drug Therapy and General Mechanisms Underlying Variability in Drug Responses13min
Variability in Drug Therapy15min
Drug Metabolism & Transport13min
Genetic Variability in Drug-Handling Molecules10min
**Inside VUMC: The Promise of Personalized Medicine1min
1 leituras
About this course10min
1 exercício prático
Introduction to Personalized Medicine12min
Semana
2
2 horas para concluir

UNIT 2: STUDYING GENETIC VARIATION

Module 3 focuses on how we study genetic variation. We'll start by looking at families and populations. Topics that will be introduced include family history and inheritance patterns, ancestry, and linkage. Then in Module 4 we shift our focus to studying the contemporary techniques and technologies used to study genetic variation, including genome-wide association and sequencing....
7 vídeos (total de (Total 104 mín.) min), 1 teste
7 videos
Ancestry: Genetic Variation Across Generations and Geography17min
Finding Disease-Associated Genes: Linkage10min
**Inside VUMC: From Phenotype to Genotype and Back: Studying Heart Disease in Families1min
Genome-Wide Association25min
Sequencing28min
**Inside VUMC: History of Sequencing Technologies1min
1 exercício prático
Studying Genetic Variation12min
Semana
3
3 horas para concluir

UNIT 3: CASE STUDIES IN PERSONALIZED MEDICINE, PART 1

In Module 5 we will begin to discuss specific cases as these apply to personalized medicine. We will first look very closely at a case of familial hypercholesterolemia as we investigate how we use genomic medicine to move from a rare disease to a common medication, using genomics to find new drug targets, and a discussion of the side effects of statin therapy. In Module 6 we will look at a collection of "high risk pharmacogenetics"cases that illustrate adverse reactions due to drug metabolism and variable drug responses....
13 vídeos (total de (Total 174 mín.) min), 1 teste
13 videos
Using Genomics to Find New Drug Targets: Familial Hypercholesterolemia16min
Muscle Pains During Statin Therapy (Myopathy)13min
HLA-Mediated Immune Reactions (Skin Rash)9min
Long QT Syndromes, Part 115min
Long QT Syndromes, Part 218min
**Inside VUMC: Studying Cardiac Arrhythmias in Cells4min
A Second Heart Attack a Month After a First15min
Headache During Venlafaxine (Antidepressant)16min
Respiratory Arrest After Tonsillectomy10min
A Bleeding Complication 5 Days After Starting Warfarin21min
**Inside VUMC: Genotyping1min
Drug Metabolism and Variable Drug Responses – Four More Examples17min
1 exercício prático
Case Studies, Part I16min
Semana
4
2 horas para concluir

UNIT 4: CASE STUDIES IN PERSONALIZED MEDICINE, PART 2

Module 7 continues our focus on case studies with a look at some cases that illustrate how personalized medicine informs treatment decisions related to specific diseases/conditions. These include cystic fibrosis, Marfan syndrome, heart failure, neuropsychiatric diseases, and diabetes. Three cases/lessons focus specifically on how genomic medicine informs testing for and treatment of cancer. ...
9 vídeos (total de (Total 119 mín.) min), 1 teste
9 videos
Marfan Syndrome11min
A Case of Idiopathic Heart Failure16min
Personalizing Care in Neuropsychiatric Disease18min
Personalizing Care in Diabetes21min
Genomics to Subtype Cancer11min
A Family Member With Breast Cancer14min
A Family Member With Colon Cancer11min
**Inside VUMC: Organizing Infrastructure to Support Genetic Testing Decisions1min
1 exercício prático
Case Studies, Part II10min
4.8
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Melhores avaliações

por NJApr 9th 2019

The course is very useful for all physicians to diagnoise the disorder and to suggest the solution for their problem and also can explain the cause of the disorder from the root that;s genome.

por VLFeb 25th 2018

This is a really great course it was very informative, interesting and well structured and I enjoyed the lessons, Prof. Roden did a really great job in this course. Thank you!

Instrutores

Avatar

Dan Roden, M.D.

Professor of Medicine and Pharmacology
Assistant Vice Chancellor for Personalized Medicine

Sobre Universidade Vanderbilt

Vanderbilt University, located in Nashville, Tenn., is a private research university and medical center offering a full-range of undergraduate, graduate and professional degrees....

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