Informações sobre o curso
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154 avaliações

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Aprox. 15 horas para completar

Sugerido: 20 hours of videos and quizzes...


Legendas: Inglês

Habilidades que você terá

BiologyMicrobiologyPublic HealthVaccine Development

100% online

Comece imediatamente e aprenda em seu próprio cronograma.

Prazos flexíveis

Redefinir os prazos de acordo com sua programação.

Aprox. 15 horas para completar

Sugerido: 20 hours of videos and quizzes...


Legendas: Inglês

Programa - O que você aprenderá com este curso

1 hora para concluir

Course Introduction

Welcome to Epidemics: the Dynamics of Infectious Diseases. This course will teach you about the variety of parasitic organisms that infect humans, animals, and plants, how these parasites spread through populations, and the various methods that we employ to control them....
3 leituras
3 leituras
Course Overview10min
Course Syllabus10min
Glossary of Terms10min
1 hora para concluir


In the first module, you will learn about the organisms that can infect us and make us sick: pathogens. We will first take a look at the various types of pathogens that exist, and then learn about what it means to be infectious, and what it means to cause disease. After that, we will cover the various methods by which pathogens can transmit from one person to the next, thereby causing an epidemic. You will learn about the most important number in all of epidemiology, R0, and why this number is so important. Finally, we will learn that microorganisms are not always harmful, but can be beneficial to us as well....
7 vídeos (total de (Total 40 mín.) min), 1 leitura, 1 teste
7 videos
Micro and Macro Parasites5min
Infection and Disease6min
Transmission Types4min
Reproductive Number4min
Epidemic Curve6min
1 leituras
Module Overview10min
1 exercício prático
Summative: Pathogens20min
1 hora para concluir


The second module of the course covers host factors that determine the outcome of infection. We will first focus on host immunity and present both the general immune capabilities—the innate immune response—that are encoded in our genes and that provide the initial response to infection and the adaptive immune response, which arises from highly specialized cells that protect against a specific pathogen. You will then learn about the ways that pathogens circumvent these two types of immunity and consider other factors that can contribute to an individual becoming infected or diseased—including genetic factors, other microbes, and how social and emotional factors influence immunity. We will then consider how infection with a microorganism causes disease and how public health officials determine whether a disease outbreak is caused by an infectious organism....
7 vídeos (total de (Total 41 mín.) min), 1 leitura, 1 teste
7 videos
Types of Immunity: Adaptive Immune System5min
Immune Evasion6min
Other Determinants of Susceptibility6min
Social Influences on Immunity4min
Pathogens and Disease6min
Detecting an Infectious Disease Outbreak6min
1 leituras
Module Overview: Hosts10min
1 exercício prático
Summative: Hosts20min
1 hora para concluir

Basics of Ecology

The third module of the course covers ecological factors that influence the dynamic patterns of infectious disease. We will discuss the conditions under which a pathogen can drive its host to extinction. We will look at how the demography of the host may allow the pathogen to persist in some populations but not others. We will talk about how host and pathogen characteristics interact to shape different temporal patterns of disease incidence at the population level and discuss the ecological consequences of infecting more than one host species....
9 vídeos (total de (Total 55 mín.) min), 1 leitura, 1 teste
9 videos
Force of Infection5min
Flu 19185min
Host Diversity, Host Range3min
Critical Community Size8min
Pathogen-Microbiome Interactions8min
The 2014 Ebola Outbreak9min
1 leituras
Module Overview: Basics of Ecology10min
1 exercício prático
Summative: Basics of Ecology20min
1 hora para concluir


Where humans live and how they are connected to each other, have strong effects on how infectious diseases can spread. In this module, you will learn about some of the related key concepts of epidemiology. After looking at some fascinating history, we’ll learn about social networks as the ultimate “road map” on which diseases can travel and we’ll talk about how the structure of the network can influence disease dynamics. After that, we’ll cover three topics that all affect infectious disease epidemiology in dramatic ways: human transport systems, population density and so-called superspreaders - individuals who can spread a disease to dozens or even hundreds of other individuals. We’ll close by identifying what information is required for disease surveillance....
8 vídeos (total de (Total 52 mín.) min), 1 leitura, 1 teste
8 videos
Social Networks5min
Structure of Networks5min
Spatial Hetergeneity5min
Movement and Modern Transportation5min
Surveillance and Disclosure5min
Co-Infection Consequences10min
1 leituras
Module Overview: Epidemiology10min
1 exercício prático
Summative: Epidemiology20min
1 hora para concluir


In module 5 of the course, you will learn about vaccination, one of the most common approaches to the prevention of epidemics. We'll first put vaccination in the context of the many types of public health interventions that that can be used to prevent or treat disease. After that you will learn about the development of the first vaccine, how vaccines work to prevent infection, and the impact that vaccination has had on the prevention of disease worldwide. After that, you will learn about how vaccination can provide protection to everyone, even the unvaccinated, in the population through "herd immunity" and how we can use the structure of social networks within populations to more efficiently achieve this herd protection. Finally we'll learn about how individuals choices about whether or not to get vaccinated can lead to impacts across the whole of the population....
7 vídeos (total de (Total 40 mín.) min), 1 leitura, 1 teste
7 videos
Discovery of the First Vaccine3min
Global Impact of Vaccination6min
How Vaccination Works7min
Herd Immunity5min
Social Networks and Targeted Vaccination6min
Vaccination Refusal5min
1 leituras
Module Overview: Vaccination10min
1 exercício prático
Summative: Vaccination20min
2 horas para concluir

Control Mechanisms

In module 6 of the course, you will learn about mechanisms involved in controlling epidemics. In these lectures, we will discuss what control mechanisms are trying to do, such as breaking the chain of transmission, and many ways by which animals and humans attempt to achieve control. These means include pharmaceutical and non-pharmaceutical interventions, appearing at individual or population levels. We will describe examples of great successes in eradication, and the reasons why control efforts fail....
10 vídeos (total de (Total 63 mín.) min), 1 leitura, 1 teste
10 videos
Social Challenges to Eradication4min
Non-pharmaceutical Interventions: Animals5min
Non-pharmaceutical Interventions: Humans 14min
Non-pharmaceutical Interventions: Humans 27min
Behavioral Avoidance6min
Controlling the Vector8min
Consequences of Control7min
Vaccination Ethics7min
New Approaches to an Old Infection5min
1 leituras
Module Objectives: Control Mechanisms10min
1 exercício prático
Summative: Control Mechanisms20min
1 hora para concluir


In module 7 of the course, we’ll look at so-called emerging infectious diseases. These are diseases that are causing new problems. They include infectious agents that are new to humanity, but also infectious agents that were once controlled and are now returning, particularly those that are evolving around formerly very effective public health tools like drugs and vaccines. This means much of the week involves a discussion of evolution. We will look at these emerging diseases and ask, where do they come from and what can be done about them? You will learn about new ideas for managing evolution, and some of the societal challenges involved. We will also look at the related question of how some diseases evolve to be nicer or nastier to their hosts....
7 vídeos (total de (Total 49 mín.) min), 1 leitura, 1 teste
7 videos
Evolution General5min
Antibiotic and Drug Resistance5min
Management of Resistance8min
Behavioral And Economic Impact5min
Evolution of Virulence8min
1 leituras
Module Overview: Emergence10min
1 exercício prático
Summative: Emergence20min
1 hora para concluir

Global Health

In this final module we explore the global context of epidemics. The world is rapidly changing with the global population increasing and the speed of travel and extent of globalization piling on the pressure of infectious diseases. In this week we set out first to explore a textbook example of disease shaped by the conditions presented by modern living: the disease SARS. We will see how high density living in cities coupled with links to wildlife diseases through markets can create a pandemic. We then explore traditional methods of disease surveillance and then more recent ones afforded to us by the web and networks made possible through google, twitter and other social media. Important to this global view is human behavior, our evolving culture and health. We will also consider emerging disease and the global pattern of diseases across our recent history and how from our earliest beginnings of global travellers we have affected the spread of diseases. Finally, we discuss disease of our food plants and how models of disease spread are developed to promote better global health. As a postscript to the course we ask the questions, so beloved of modern media, could we become zombies?...
9 vídeos (total de (Total 55 mín.) min), 1 leitura, 1 teste
9 videos
Disease Surveillance - Classical7min
Disease Surveillance - Digital5min
Culture and Health5min
Emerging Disease Issues7min
Crop Diseases and Food Security5min
Global Pattern of Parasite Biodiversity4min
Models of Infectious Diseases7min
1 leituras
Module Overview: Global Health10min
1 exercício prático
Summative: Global Health20min
4 horas para concluir

Ask Us Anything Videos

The videos accessible in this module are responses to questions that have been posed in previous sessions of this course. We invite you to look around here as an additional resource to answer questions you might have yourself or explore topics that pique your interest. ...
36 vídeos (total de (Total 261 mín.) min)
36 videos
What Does It Mean to Be Infectious?4min
What is the Impact of Prior Infections on Susceptibility to New Pathogens?5min
What Ended the Plague? What Can We Learn About Pandemics?5min
Can Behavior Contribute to Susceptibility?6min
Marilyn Roosinck and What’s Different about Plant Epidemiology?8min
Can Plants be Vectors of Disease?4min
What are Other Determinants of Susceptibility?5min
Can Pathogens Change Host Function?5min
Immune System Conflict6min
Eric Harvill and What is the Whole Micro-Biome, Pro-Biotic, Good Bacteria Thing?6min
Why Can't Our Antibodies Mutate Like Antigens?4min
How Does Microbiome Exchange Therapy Work?8min
What are the Best Strategies to Combat Multi-Species Infections?7min
How Relevant is the Concept of Critical Community Size?7min
Isabella Catadori and the Translation of Her Lab Work into the Field5min
Examples of Co-Infections and How They Change Epidemiology of Human Infections6min
Super-Shedders v. Super Spreaders and the Pareto Principle6min
The Role of Social Media in Epidemiology and how Information is Disseminated8min
Dr. Vivek Kapur and What Do We Need to Know about Development and Implementation of New Vaccines?9min
Why Don't We Have Vaccines for Everything?8min
Why Don't We Use Targeted Vaccinations?7min
What Are the Benefits of So-Called Gain-of-Function Experiments?11min
Dr. Moriah Szpara and How/Why do viruses like Varicella and Herpes Re-activate Themselves?7min
What are the Challenges to the Eradication of Pathogens and Setting Eradication as a Goal?6min
How Does Stress Affect Susceptibility and the Expression of Disease?6min
Has there been a Collective Change in Human Behavior in Response to Sexually Transmitted Diseases?9min
What can we do to minimize selection for resistance in vectors?8min
Genetic engineering of vectors? pt.17min
Genetic engineering of vectors? pt.27min
What is the role of climate change in disease emergence?8min
What can we learn from antibiotic and vaccine use in agriculture? 7min
Dr. Craig Cameron and What do We Mean by 'Antivirals?'8min
What is it About Polio?9min
What About the One Health Concept?7min
What is the Next Big Thing?8min
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Melhores avaliações

por DBApr 23rd 2016

Can't fault this course at all and nor would I want to. Very interesting, brilliantly presented and the range of experts really enhanced it. It was engaging and made me keen to find out more.

por DJMay 13th 2017

It is a wonderful course , I have gain and updated my Knowledge in the area of Epidemics and Infectious Disease, Thanks to the Course organizers and most effective presentations . Dr Shivaji



Dr. Ottar N. Bjornstad

Professor of Entomology and Biology
Department of Biology

Dr. Rachel A. Smith

Associate Professor
Department of Communication Arts & Sciences and Human Development & Family Studies

Dr. Mary L. Poss

Professor of Biology
Department of Biology

Dr. David P. Hughes

Assistant Professor of Entomology and Biology
Department of Biology

Dr. Peter Hudson

Willaman Professor of Biology
Department of Biology

Dr. Matthew Ferrari

Assistant Professor of Biology
Department of Biology

Dr. Andrew Read

Alumni Professor in the Biological Sciences, and Professor of Entomology
Center for Infectious Disease Dynamics

Dr. Marcel Salathé

Assistant Professor of Biology
Department of Biology

Sobre Universidade Estadual da Pensilvânia

Founded in 1855 as Pennsylvania's only land-grant university, The Pennsylvania State University combines academic rigor with a vibrant campus life. A nationally recognized Research-I institution, Penn State teaches students to be leaders with a global perspective. Supporting not only the citizens of our Commonwealth, Penn State engages in collaborative activities with industrial, educational, and agricultural partners in the United States and abroad to generate, disseminate, integrate, and apply knowledge that is valuable to society....

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