Kidney transplantation is a major advance of modern medicine which provides high-quality of life for patients with end-stage renal disease. What used to be an experimental, risky, and very limited treatment option more than 50 years ago is now routinely performed in many countries worldwide. The number of renal transplants is expected to rise sharply in the next decade since the proportion of patients with end stage renal disease is increasing.
oferecido por
Universidade de Leiden
Leiden University Medical Center
Clinical Kidney, Pancreas and Islet Transplantation
Universidade de LeidenInformações sobre o curso
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Resultados de carreira do aprendiz
33%
comecei uma nova carreira após concluir estes cursos
25%
consegui um benefício significativo de carreira com este curso
Certificados compartilháveis
Tenha o certificado após a conclusão
100% on-line
Comece imediatamente e aprenda em seu próprio cronograma.
Prazos flexíveis
Redefinir os prazos de acordo com sua programação.
Nível intermediário
Aprox. 35 horas para completar
Inglês
Legendas: Inglês
Resultados de carreira do aprendiz
33%
comecei uma nova carreira após concluir estes cursos
25%
consegui um benefício significativo de carreira com este curso
Certificados compartilháveis
Tenha o certificado após a conclusão
100% on-line
Comece imediatamente e aprenda em seu próprio cronograma.
Prazos flexíveis
Redefinir os prazos de acordo com sua programação.
Nível intermediário
Aprox. 35 horas para completar
Inglês
Legendas: Inglês
oferecido por
Universidade de Leiden
Leiden University is one of Europe's foremost research universities. This prominent position gives our graduates a leading edge and prepares them for careers both within and outside of academia. Leiden University is the oldest university in the Netherlands, founded in 1575. Our motto is: Praesidium Libertatis (Bastion of Liberty) - Freedom of spirit, thought and expression. Leiden University has a campus in Leiden and The Hague, with 7 faculties, 47 Bachelor Programmes, 79 Master Programmes and nearly 30,000 students.
Leiden University Medical Center
Programa - O que você aprenderá com este curso
2 horas para concluir
Welcome to the course
Great that you are joining us! In this course you will learn about clinical kidney, pancreas and islet transplantation and its challenges. Before you start with studying we invite you first go through our introduction module and introduce yourself in the forum to meet your fellow learners. Medical professionals can receive Continuing Medical Education (CME) credit for this course. Information on CME credit and how to obtain credit can be found in our CME credit module. If you encounter any difficulties while studying, please let us know in the forum. For technical difficulties or questions regarding the course certificate, you can always contact the Coursera Learner Helpdesk. Good luck & we hope you enjoy studying in this course!
2 horas para concluir
2 vídeos (Total 4 mín.), 8 leituras
8 leituras
About us: Introduction to the Team5min
Leiden University: Facts & Figures10min
Tips for studying online5min
Community Guidelines 5min
What is your learning path?5min
CME information10min
How to apply for CME credit15min
CME FAQs15min
6 horas para concluir
Before the Transplant
Welcome to this first module of the course! We will answer important questions before transplantation. These include: why is transplantation the preferred option for patients with end stage renal disease? What are the immunological barriers for transplantation? And what are the selection criteria before transplantation? Unique 3D movies about the different immunological tests will help you to understand the concepts. There are also optional lectures, including a fascinating movie about the Eurotransplant allocation system and patient/donor interviews. At the end of the module we will link the contents you have learned to clinical patient cases, patient - donor interviews and a quiz. You can find each other on the discussion forum. With the e-tivities you can apply your knowledge. In the honors lessons more in depth immunological testing and pre transplant screening can be obtained. The lesson also includes peer reviews about important preclinical questions. Have fun and good luck with the first module!
6 horas para concluir
11 vídeos (Total 79 mín.), 4 leituras, 3 testes
11 videos
The Kidney in Health and Disease5min
Options if Kidneys Fail5min
Immunogenetics7min
Introduction to the Immune System6min
The Humoral Immune System6min
Histocompatibility7min
Cases from Daily Practice - Patient Selection7min
Eurotransplant Company Film 'More than a Match'13min
Interview: Transplant Recipient and Donor: Part 110min
Epitopes6min
4 leituras
Glossary20min
References30min
HLA Epitope Matching is the Future30min
HLA Antibody Detection: Not All Antibodies are the Same30min
2 exercícios práticos
Check your knowledge30min
Check your knowledge30min
8 horas para concluir
The Procedure and the Patient
Now you know the factors of importance before transplantation, including the immunological barriers and important aspects for patient selection, we can focus on challenged patient groups and on surgical procedures. What does a kidney, pancreas and islet transplantation surgical procedure look like? What is important? And what are the key aspects in elderly patients, patients with diabetes and immunological challenged patients. We have unique visulisations, 360 virtual reality videos and a game about a patient case. Advanced readings will invite you to look at the different subjects in more depth. At the end of the module there are interviews about a patient with diabetes and the transplant recipient and donor to illustrate the impact of life. You can discuss patient cases on the forum together with your peers. In the honors lesson you can apply knowledge about more in depth immunological, surgical and metabolic challenges and living kidney donation. Let’s start and we hope you will enjoy this module.
8 horas para concluir
14 vídeos (Total 111 mín.), 7 leituras, 3 testes
14 videos
Immunological Challenged Patient: ABO Incompatible Transplants6min
Immunological Challenged Patient: Highly Sensitized Patient6min
The Diabetic Patient10min
The Elderly Patient6min
Organ Procurement and Preservation9min
Kidney Transplant Surgery7min
Simultaneous Pancreas Kidney & Islet Transplantation15min
A: Cases from Daily Practice: Different Choices for Different Diabetic Patients5min
B: Cases from Daily Practice: Different Choices for Different Diabetic Patients6min
Interview: Patient with Diabetes14min
Interview: Transplant Recipient and Donor: Part 24min
B Cell Replacement and Diabetes Type II11min
Surgical Challenged Patients6min
7 leituras
Introduction to Watching 360 VR Videos10min
Serious Game: A Patient with Immunological Challenges30min
Glossary10min
References5min
Highly Sensitized Patients: The AM Program30min
Additional Challenged Transplant Recipients30min
Living Kidney Donation30min
2 exercícios práticos
Check your knowledge30min
Check your knowledge20min
10 horas para concluir
Early Challenges in Transplantation
You are now familiar with the basic knowledge about challenges in transplant recipients and the surgical transplant procedures. Once the transplantation has been successful, it doesn’t mean everything is stable. What are actually the graft survival data? Which challenges do we face in the first months? How can we tackle these challenges? 3D movies about early surgical challenges and about the targets for immunosuppressives, including cell therapy, will help you to understand the concepts. In addition, we invite you to master the advanced knowledge and to give your opinion in the patient cases in the forum. There is also a serious game about a patient case. Can you solve the challenges? And can you think of a scenario for the game and help us with building? We will make a game of the best scenario, which will be incorporated in the course. In the honors lesson you can learn in more detail about immunological concepts, including the complement system. A patient case will help to show you the importance of this knowledge. Good luck with this module and happy learning!
10 horas para concluir
12 vídeos (Total 95 mín.), 9 leituras, 3 testes
12 videos
Surgical Challenges in the Early Period5min
Ischemia Reperfusion Injury6min
Cellular Rejection8min
Antibody Mediated Rejection6min
Immune Suppression10min
Novel Therapeutics: Cell Therapy after Transplantation8min
Cases from Daily Practice A - Patient Cases with Early Challenges6min
Cases from Daily Practice B - Patient Cases with Early Challenges6min
Interview Transplant Recipient & Donor: Part 38min
The Complement System and Transplantation11min
Cases from Daily Practice: Patient Case with an Early Challenge7min
9 leituras
Serious Game: Interactive Patient Case30min
Optional - Immunesuppressive Regimens and Toxicity Profiles1h
Biomarkers40min
Therapeutic drug monitoring of immunosuppressive drugs1h
Glossary10min
References5min
A closer Look at Antibody Mediated Rejection30min
Innate Immunity and Impact on Transplantation30min
Molecular Insights into Cellular Rejection30min
2 exercícios práticos
Check your knowledge30min
Check your knowledge30min
7 horas para concluir
Late Challenges in Transplantation
Now you’ve learned about the challenges in the early period after transplantation. But what about the late period? What is the long term patient and allograft survival? Have we improved in the last decades? What are the main causes for morbidity and mortality? And can we reach tolerance in the future? We invite you to give your opinion in the patient cases and to discuss it on the forum. There are also advanced readings to look at additional subjects, including recurrence of the kidney disease after transplantation, the organization of dermatological care for the transplant recipient and the role of the patient himself in the whole process. The interview about tolerance gives you insight why pregnancy is of interest to understand the concept of tolerance and which steps have been made from lab research to a clinical protocol. In the honors lesson late challenges will be discussed in more detail, with a focus on infections, recurrence of the kidney disease after transplantation and tolerance. Have fun and good luck with this last module.
7 horas para concluir
12 vídeos (Total 96 mín.), 5 leituras, 6 testes
12 videos
Infections: Overview and CMV infection8min
Infections: BK and EBV infection7min
Malignancies8min
Late Challenges after Pancreas and Islet Transplantation8min
Post Transplant Diabetes Mellitus8min
Cardiovascular Disease7min
Tolerance: Interview with Prof. Claas (LUMC) and Prof. Wood (Oxford)13min
Cases from Daily Practice A - Patient Cases with Late Challenges5min
Cases from Daily Practice B - Patient Cases with Late Challenges6min
Recurrence of Kidney Disease after Transplantation8min
Vaccination and Transplantation8min
5 leituras
Pneumocystis jirovecii10min
Glossary10min
References5min
Skin Diseases after Transplantation and Dermatological Aftercare30min
Tolerance in more Detail30min
5 exercícios práticos
Check your knowledge30min
Patient Case 1: Enhanced Glucose after SPK15min
Patient Case 2: Hyperglycemia after Islet Transplantation15min
Patient Case 3: A Complication after Pancreas-alone Transplantation15min
Check your knowledge20min
1 hora para concluir
Final Quiz
We hope you have enjoyed all the modules. Good luck with the final quiz!
1 hora para concluir
2 exercícios práticos
Final Exam30min
Final Honours Exam30min
Avaliações
Principais avaliações do CLINICAL KIDNEY, PANCREAS AND ISLET TRANSPLANTATION
por SW26 de Dez de 2016
Wonderful course. Great instruction on very interesting topics. Videos support learning and a good amount of information every week. Thanks for the organization and delivery of this course.
por AE23 de Mai de 2017
THE BEST COURSE I have taken in COURSERA GREAT LECTURERS , BEST VIDEOS, AND VERY ORGANIZED\n\n3D movies are really fantastic\n\nHope to join in future sessions to get better scores
por MK1 de Abr de 2016
A very well designed and delivered course. I found it very useful, very well structured and the content was relevant and in the right amount of detail. Excellent course.
por AS3 de Jul de 2019
It was a helpful course, with very good animations and great explanations. I would very much like to benefit from an advanced course on the same topic. Thank you all!
Perguntas Frequentes – FAQ
Quando terei acesso às palestras e às tarefas?
O acesso a palestras e tarefas depende do tipo de inscrição. Se você participar de um curso como ouvinte, você poderá ver quase todo o conteúdo do curso gratuitamente. Para acessar tarefas valendo nota e obter um Certificado, você precisará adquirir a experiência do Certificado, durante ou após a participação como ouvinte. Se você não vir a opção de participar como ouvinte:
- o curso pode não oferecer essa opção. Você pode experimentar um teste gratuito ou solicitar o auxílio financeiro.
- Em vez disso, o curso pode oferecer 'Curso completo, sem Certificado'. Com esta opção, é possível ver todo o conteúdo do curso, enviar as avaliações necessárias e obter uma nota final. Isso também significa que você não poderá comprar uma experiência de Certificado.
O que recebo ao adquirir o Certificado?
Quando você adquire o Certificado, ganha acesso a todo o material do curso, incluindo avaliações com nota atribuída. Após concluir o curso, seu Certificado eletrônico será adicionado à sua página de Participações e você poderá imprimi-lo ou adicioná-lo ao seu perfil no LinkedIn. Se quiser apenas ler e assistir o conteúdo do curso, você poderá frequentá-lo como ouvinte sem custo.
Is financial aid available?
Sim, a Coursera oferece auxílio financeiro aos alunos que não podem pagar a taxa. Faça a solicitação clicando no link Auxílio financeiro, abaixo do botão "Inscreva-se" à esquerda. Você será solicitado a preencher um formulário e será notificado se for aprovado. Saiba mais.
What are CME credits?
Continuing Medical Education (CME) consists of educational activities that aim to maintain, develop, or increase the knowledge, skills, and professional performance in order to maintain competence and learn about new and developing areas of the medical field. Content for these programs is developed, reviewed, and delivered by faculty who are experts in their individual clinical areas. In various countries, a certain amount of CME-credit hours must be obtained by medical professionals to maintain their licenses.
For this course it is possible to obtain 5, 9 or 13 CME credit points. For more information on how to obtain these points we like to refer to the "Additional introduction for obtaining CME credit" module in week 1 of the course
Can I apply for CME credits if I have already finished the course previously?
Yes, if you have already done the course previously and obtained the Coursera official Course Certificate as proof we encourage you to apply for the CME credits. You can obtain 5 or 9 CME as follows:
1. Sign up for the course at “Boerhaave Continuous Medical Education” (https://www.boerhaavecontinuousmedicaleducation.com/)
2. Upload your Verified Certificate from Coursera (without honors 5 CME or with honors 9 CME). Pay the contribution according to “Boerhaave Continuous Medical Education." They will provide you with the instructions and add the CME credits to GAIA (Dutch participants) and/or provide you with a CME certificate (international participants)
Ganharei créditos universitários por concluir o curso?
Este curso não oferece créditos universitários, mas algumas universidades podem aceitar certificados de cursos que podem ser convertidos em créditos. Entre em contato com sua instituição para saber mais. Com os cursos on-line e os certificados Mastertrack™ do Coursera, é possível ganhar créditos universitários.
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