This MOOC is designed principally for practicing teachers who are wondering exactly how they can incorporate teaching and assessment of 21st century skills into their classrooms, labs or workshops. It will also be useful to trainee teachers, school leaders, teacher educators and curriculum and assessment specialists, providing them with an understanding of the challenges associated with teaching and assessment of 21st century skills. This course explains the social and cognitive skills that are known as 21st century skills. It reviews how they can be represented in the curriculum, in terms of developmental progressions. It also explores how teachers can recognise these skills in students, how the level of skill of a learner can be assessed, and then how learners can be supported to develop their skill. In this course we work through two detailed examples of 21st century skills. The first is collaborative problem solving, a 21st century skill which combines the capacities of collaboration, problem solving, critical thinking and communication. The second skill is a meta-cognitive skill of knowing how to learn in a MOOC. In each example, you will explore how to understand the nature of each skill from a teaching perspective, how to teach it, and how to assess it. These two examples show how any 21st century skill can be tackled in the classroom. The approach to teaching and assessment in this course derives from the application of a developmental, evidence-based, clinical approach to teaching practice. The course provides a mix of theory and practice, of thinking and doing, and opportunities to share ideas, experience and resources with other participants. Join Emeritus Professor Patrick Griffin and the team from the Assessment Research Centre, University of Melbourne in a Massive Open Online Course (MOOC) on the Assessment and Teaching of 21st Century Skills, hosted on Coursera.