2.2.4 Simple and complex cells-I

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Do curso por Peking University

Advanced Neurobiology II

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Peking University

Advanced Neurobiology II

49 ratings

Hello everyone! Welcome to advanced neurobiology! Neuroscience is a wonderful branch of science on how our brain perceives the external world, how our brain thinks, how our brain responds to the outside of the world, and how during disease or aging the neuronal connections deteriorate. We’re trying to understand the molecular, cellular nature and the circuitry arrangement of how nervous system works. Through this course, you'll have a comprehensive understanding of basic neuroanatomy, electral signal transduction, movement and several diseases in the nervous system. This advanced neurobiology course is composed of 2 parts (Advanced neurobiology I and Advanced neurobiology Il). They are related to each other on the content but not on scoring or certification, so you can choose either or both. It’s recommended that you take them sequentially and it’s great if you’ve already acquired a basic understanding of biology. Thank you for joining us!

Na lição

Perception: Auditory

2.1.1 Center-Surround Receptive Field11:48

2.2.2 The LGN6:00

2.2.3 LGN and the visual pathway10:44

2.2.4 Simple and complex cells-I7:55

2.2.5 Simple and complex cells-II10:40

2.2.6 Colors6:13

Conheça os instrutores

Chenjian Li
Professor
School of Life Sciences
Donggen Luo
Research Fellow
School of Life Sciences
Yan Zhang
Professor
School of Life Sciences, Peking University

We talked about actually the signals around receptor field in the retina,

right?

And they house this information, actually process it in the brain.

There's a very important topic.

And from this study,

then you can really try to understand how the brain works, right?

Now, these two gentlemen, Hubel and

Wiesel, and that they did a beautiful work,

including the [FOREIGN] and

also a quite important the electrophysiology

of the receptive field started.

And that they got the 1981 Noble Prize in Physiology and Medicine.

Let's look at their approach for this study.

The approach, actually, they want to study the visual cortex function, okay?

And visual cortex, how can you study it, right?

So typically they use a cat.

[FOREIGN] And

you open, of course the cat is fixed here.

[FOREIGN] okay?

And then, you insert a electrode into the visual cortex.

Visual [FOREIGN], just so you can input the default, right?

Layout for C, for example.

And then, you have a TV monitor.

To show the light stimulation to the cat.

The cat [FOREIGN] quite

disappointed at the beginning.

They try to use the light because in the In the retina,

the study actually just uses a light, a spot stimulation.

You can get a response from the neuron.

But when it went to trial, they used the light stimulation.

One light here.

One light there.

Even here across the whole screen.

And those neurons, there should

be numerous response, okay?

Laser is fun actually, very special.

Those cells actually, can only respond when you have a light bar.

Just so you [FOREIGN].

Then you can see it. [FOREIGN]

The cell [FOREIGN].

And if you [FOREIGN].

For example, this one.

You change the direction and the cell doesn't care [FOREIGN].

[FOREIGN] special, okay?

So these are from the same cell recording,

then you cannot [FOREIGN] only this direction

the response system the strongest one.

And then [FOREIGN] and

[FOREIGN], okay?

How will you think about this observation, if you get the recording,

get these kind of results?

[FOREIGN] This is what we observed.

No.

They then actually think very hard

about this observation, okay?

So because in the cell, as we said,

the receptive field is a center [FOREIGN] you know, send us around.

[FOREIGN]

In either case.

[FOREIGN] Cortex, so dramatic different.

Of course, maybe

a lot of computation

[FOREIGN] [FOREIGN]

If take a look at the,

we took a look at

the photo receptor.

[FOREIGN] So,

in the bipolar cell,

the computation

mainly happens

by the horizontal

cell, right,

making circles

around.

[FOREIGN] the cell is near the same is around.

But to this stage then became

a directions important and also you need a light bar.

[FOREIGN]

Of course, then if you want to study

system mechanisms [FOREIGN], what will you do?

It's actually, let's first actually record from the LGN, right?

Because we know cell is like a bar, and this cell is like, you need a.

But then in the middle there was LGN cell, right?

So let's record from the LGN.

And actually, when people did the recording from the LGN, those neurons,

the receptive field is exact the same as the cell.

Sent us around, okay?

So then the question comes down to how the LGN,

the input to this visual cortex, just one synapse.

Then you make a transformation, right?

Can you imagine a way, especially to achieve which is

centers around to this this light bar, and also direction sensitive receptor field.

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