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Voltar para Whole genome sequencing of bacterial genomes - tools and applications

Comentários e feedback de alunos de Whole genome sequencing of bacterial genomes - tools and applications da instituição Universidade Técnica da Dinamarca (DTU)

4.6
349 classificações
88 avaliações

Sobre o curso

This course will cover the topic of Whole genome sequencing (WGS) of bacterial genomes which is becoming more and more relevant for the medical sector. WGS technology and applications are high on international political agenda, as the classical methods are being replaced by WGS technology and therefore bioinformatic tools are extremely important for allowing the people working in this sector to be able to analyze the data and obtain results that can be interpreted and used for different purposes. The course will give the learners a basis to understand and be acquainted with WGS applications in surveillance of bacteria including species identification, typing and characterization of antimicrobial resistance and virulence traits as well as plasmid characterization. It will also give the opportunity to learners to learn about online tools and what they can be used for through demonstrations on how to use some of these tools and exercises to be solved by learners with use of freely available WGS analysis tools . By the end of this course you should be able to: 1. Describe the general Principles in typing of Bacteria 2. Give examples of the applications of Whole Genome Sequencing to Surveillance of bacterial pathogens and antimicrobial resistance 3. Apply genomic tools for sub-typing and surveillance 4. Define the concept of Next-Generation Sequencing and describe the sequencing data from NGS 5. Describe how to do de novo assembly from raw reads to contigs 6. Enumerate the methods behind the tools for species identification, MLST typing and resistance gene detection 7. Apply the tools for species identification, MLST typing and resistance gene detection in real cases of other bacterial and pathogen genomes. 8. Describe the methods behind the tools for Salmonella and E.coli typing, plasmid replicon detection and plasmid typing 9. Utilize the tools for Salmonella and E.coli typing, plasmid replicon detection and plasmid typing in real cases of other bacterial and pathogen genomes. 10. Explain the concept and be able to use the integrated bacterial analysis pipeline for batch analysis and typing of genomic data 11. Demonstrate how to construct phylogenetic tree based on SNPs 12. Apply the phylogenetic tool to construct phylogenetic trees and explain the relatedness of bacterial or pathogen strains 13. Describe how to create your own sequence database 14. Utilize the MyDbFinder tool to detect genetic markers of interest from whole genome sequencing...

Melhores avaliações

MB

Jun 10, 2019

Excellent course with a wealth of information about tools and applications of whole genome sequencing. Presented in a very lucid and interesting manner, very crispy and simplified course.

XL

Jun 30, 2019

The course is using cutting-edge genome sequencing technology and the authentic software to showcasing the applications and tools of genome sequencing. It is a great chance to learn it.

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1 — 25 de {totalReviews} Avaliações para o Whole genome sequencing of bacterial genomes - tools and applications

por Robert F

Jan 28, 2019

This course is mostly just an advertisement for the particular tools created by the CGE. It would have benefited from deeper explanations of the algorithms at many points. It didn't really build skills, though I am certainly more aware of the breadth of their online tools now.

por Sören W

Jan 07, 2019

It is basically a commercial for their tools. Not much content to learn.

por Douglas A H

Dec 29, 2017

I quite liked the instructors, but after the first few lessons, the course essentially becomes an advertisement/user manual for their university's (admittedly free) online software tools.

por Kumar v

Mar 17, 2019

Course contains relevant application based material. It was quite helpful.

por Pham T T T

Sep 17, 2017

Thank you great team from DTU, I get to understand NGS via your detailed explanation and useful demonstration as well as example exercise. Cheers

por Erica Y

Oct 01, 2018

Good course for a beginner. Generally, help me understand whole genome sequencing of bacteria. Will follow other course that they have provide.

por Claudia M d l P

Aug 27, 2019

Muy buen curso para iniciar con el análisis de secuencias masivas de cepas que pudieran estar implicadas en brotes epidemiológicos. Felicidades

por Vanessa C d C L

Jan 14, 2018

This is a very interesting course, it's practical and simple to follow and I've learned a lot about whole genome sequencing and its techniques.

por Marwa M M B

Aug 19, 2017

It is totally beneficial course for those who are working in epidemiology, however; I was expected to learn different tools for species and microbial communities identification.

por Jana M

Dec 15, 2018

Great course, but very challenging. You need to be advanced in biology to do this course.

por A A A E

Jan 08, 2019

applications

por Kira K

Dec 04, 2018

This is a great class presenting a user-friendly web tool CGE pipeline that is ready to help all researches with their bioinformatics data. It can even build phylogenetic trees!

And I loved a small detective game at the end of the course when we needed to process unknown bacteria sequences to see if it was a real outbreak and what antibiotics were able to stop it!

A lot of thanks to the team!

por MUTSHIENE D E

Mar 29, 2019

Great and very insightful course. It really shed light on many aspects on whole genome sequencing

por Carlos H C

Nov 20, 2017

A clear and very didactic course on the tools that DTU offers to analyze genomes. Thanks for the classes!

por Valourstar M

Nov 15, 2017

developing skills in sequencing techniques

por 俞骅

Jul 05, 2018

简单明了,适合初学者和做细菌分型溯源的生物学家

por David M M

Apr 11, 2018

Learn the basics of WGS and how to use different tools for data analysis: species identification, plasmid search, resistance genes search, serotyping... All with a good structure and very well explained.

por Marc B F

May 02, 2018

The tools provided are very interesting and easy to use

por Moayad M A

Aug 21, 2017

very easy and interactive

por Rafael P

Jun 03, 2018

Great Course!, congratulations!

por Heba M M

Oct 14, 2017

Good course, with amazing hands-on practice. Thanks it was really helpful.

por sandeep K

May 18, 2018

The contents of the course were really very good and with loads of knowledge. Thank you very much for improving my knowledge in this area.

por Manikandan M

Oct 16, 2017

GOOD ONE TO GET KNOWLEDGE ABOUT WHOLE GENOME SEQUENCING AND BACTERIAL SUB TYPING

por Adithya A

May 23, 2018

EXCELLENT COURSE GOOD FOR ANY ONE WHO HAS A BASIC KNOWLEDGE ON GENETICS

por Opeyemi U L

Feb 02, 2018

The module was easy to follow and the class exercises made it very easy to understand. I will highly recommend this course to microbiology students especially the ones without prior knowledge of basic bioinformatics for epidemiological study of bacterial infections