Informações sobre o curso
4.8
680 classificações
184 avaliações
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100% online

Comece imediatamente e aprenda em seu próprio cronograma.
Prazos flexíveis

Prazos flexíveis

Redefinir os prazos de acordo com sua programação.
Horas para completar

Aprox. 31 horas para completar

Sugerido: 16 hours...
Idiomas disponíveis

Inglês

Legendas: Inglês
100% online

100% online

Comece imediatamente e aprenda em seu próprio cronograma.
Prazos flexíveis

Prazos flexíveis

Redefinir os prazos de acordo com sua programação.
Horas para completar

Aprox. 31 horas para completar

Sugerido: 16 hours...
Idiomas disponíveis

Inglês

Legendas: Inglês

Programa - O que você aprenderá com este curso

Semana
1
Horas para completar
2 horas para concluir

Brain Excitements for the 21st Century

Welcome to synapses, neurons and brains!...
Reading
8 videos (Total 74 min), 5 leituras
Video8 videos
Welcome Words and Great Thinkers9min
The Blossoming of the Brain in the World7min
The Connectomics10min
Brainbow8min
Brain Machine Interface BMI16min
Optogenetics7min
Simulation of the Brain - Blue Brain Project8min
Reading5 leituras
About the Course10min
Course Staff10min
Course Information10min
How to Use Discussion Forums10min
Lecture Slides10min
Semana
2
Horas para completar
2 horas para concluir

The Materialistic Mind - Your Brain's Ingredients

This module's purpose is to acquaint you with "The materialistic mind – your brain’s ingredients". You will become intimately acquainted with the beauty and variety of neurons – the elementary building block/microchips of the brain. We will highlight a big controversy between two great anatomists (Ramon y Cajal and Camillo Golgi) who both received the Nobel Prize in 1906. They asked whether the neuron is a separate “independent” unit (like other cells in other tissues) or whether it is part of a continuum? We will next discuss the neuron as an input-output device and highlight a key property of the nervous system, namely that neurons connect to each other via a wonderful devise called “synapse”....
Reading
8 videos (Total 82 min), 1 leitura, 1 teste
Video8 videos
The Neuron Doctrine9min
The Neuron as I/O Device Part I8min
The Axon14min
The Dendrite8min
Neuron Type11min
The Synapse14min
The Neuron as I/O Device Part II7min
Reading1 leituras
Lecture Slides10min
Quiz1 exercício prático
Brain Excitements for the 21st Century and The Materialistic Mind28min
Semana
3
Horas para completar
2 horas para concluir

Electrifying Brains –Passive Electrical Signals

In this module we will discuss the "Electrifying brain – passive electrical signals". We will show that neurons are electrical device and learn what enables neurons to become “electrifying”. Here we will describe only the passive (vs. active) electrical properties of neurons. We will show that, at the quiescent state, the difference in electric potential across the cell’s membrane is always negative inside the cell (“the “resting potential”); we next show that the membrane behaves like an electrical (resistance-capacitance) RC circuit and highlight the notion of “membrane time constant” and, consequently, the ability of neurons to summate (in time) successive (synaptic) inputs (“electrical memory”) – a fundamental mechanism utilized by the brain. We will also show that when the synapse is activated, it generates an analog electrical signal (“the post-synaptic potential”, PSP) in the receiving (“post-synaptic”) cell. Most interestingly, there are two types of synapses in the brain – “excitatory” and “inhibitory” – we will discuss how these two opposing signals interact in the receiving ``neuron. This module is more technical than the more descriptive first two lessons; we encourage those of you who are not familiar with basic electricity (resistance, capacitance, Ohms law and Kirchoff’s law) to read about these in the sources links for this week’s lecture....
Reading
11 videos (Total 105 min), 1 leitura, 1 teste
Video11 videos
The Voltage Equation for the Passive Cell9min
The Membrane Time Constant14min
Temporal Summation9min
The Resting Potential8min
The Synaptic Potential Part 19min
The Synaptic Conductance6min
The Synaptic Battery10min
The Synaptic Potential Part 28min
The Voltage Equation for the Synapse and EPSP and IPSP13min
Summary3min
Reading1 leituras
Sources for Lesson 310min
Quiz1 exercício prático
Electrifying Brains –Passive Electrical Signals22min
Semana
4
Horas para completar
2 horas para concluir

Electrifying Brains – Active Electrical Spikes

In this module we are covering "Electrifying brains – active electrical spikes". In the previous module we learned that: 1-neurons are electrical devices, 2 - that the membrane behaves as an RC circuit, 3 - that synapses operate by opening a new cross-membrane conductance attached with a battery. In the present module we will proceed to deal with the active electrical aspects of neurons. Synaptic inputs are the elementary (input) sources to neurons and, typically, many (excitatory) of them are required to summate (“temporal summation”) to generate a highly (“all or none”) output signal – the notorious spike (or “action potential”). In our current understanding, sensory, motor, emotional, etc., information is represented by a particular set of neurons that “fire” these spikes. So no movies or music in your brain only spikes representing (coding for) these movies and music. We will focus on the membrane mechanisms underlying the generation of the spike and in particular on the model of Hodgkin & Huxley for the spike which is probably the most fundamental and beautiful model in neuroscience. Hodgkin & Huxley received the Nobel Prize in 1963. ...
Reading
5 videos (Total 80 min), 1 leitura, 1 teste
Video5 videos
The All or None Spike and the Voltage Clamp11min
Membrane Currents Underlying the Spike14min
Modeling the Membrane Currents14min
The H&H Spike Model24min
Reading1 leituras
Lecture Slides10min
Quiz1 exercício prático
Electrifying Brains – Active Electrical Spikes26min
4.8
184 avaliaçõesChevron Right
Benefício de carreira

83%

consegui um benefício significativo de carreira com este curso
Promoção de carreira

14%

recebi um aumento ou promoção

Melhores avaliações

por AAug 14th 2017

Excellent teaching by Sir. He has created one more enthusiast in the journey of decoding Human Brain. Thank you Sir, getting my basics clear and this will help me to be better Neuro/AI researcher.

por DDSep 18th 2015

It is a very interesting and well-done course about neurobiology. Prof. Sedev has many interactive tasks and he tries to explain details as easy as possible. All in all it is understandable.

Instrutores

Avatar

Idan Segev

Professor
Computational Neuroscience

Sobre Hebrew University of Jerusalem

Ranked among the top academic and research institutions worldwide, the Hebrew University of Jerusalem is Israel's leading university and premier research institution. Serving 23,000 students from 70 countries, the Hebrew University produces a third of Israel’s civilian research and is ranked 12th worldwide in biotechnology patent filings and commercial development. The Hebrew University was founded in 1918 by visionaries including Albert Einstein, Sigmund Freud, Martin Buber and Chaim Weizmann. It is located on three campuses in Jerusalem and a fourth in Rehovot. Visit the website at http://new.huji.ac.il/en. Join our online learners community at https://www.facebook.com/groups/hujimooc/. ...

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