The neuroscience of drugs for therapy, for prevention, and for recreation. Drug addiction and drug abuse. You’ll learn the prospects for new generations of medications in neurology, psychiatry, aging, and treatment of substance abuse.
As Drogas e o Cérebro
oferecido por
Caltech – Instituto de Tecnologia da CalifórniaCaltech - Instituto de Tecnologia da Califórnia
Programa - O que você aprenderá com este curso
Semana
13 horas para concluir
Week 1. Organization and Overview
The description goes here
11 vídeos (total de (Total 123 mín.) min), 1 teste
11 videos
2. Organization and Overview, weeks 4- 7 9min
3. What is a Drug? 13min
4. Drug Entry Into the Nervous System 12min
5. Introduction to Drug Receptors 11min
6. More about receptors as proteins 13min
7. Introduction to Mammalian Brains 9min
8. Techniques for Studying the Brain 10min
9. Botulinum toxin 9min
10. Origin of the Resting Potential 10min
11. Electrical Aspects of Ion Channels 8min
1 exercício prático
Quiz on miniLectures 1-1136min
Semana
22 horas para concluir
Week 2. Dose-response Relations
The description goes here
10 vídeos (total de (Total 92 mín.) min), 1 teste
10 videos
2 Quantitative Approaches, Agonist Only 10min
3 Agonists plus Antagonists 7min
1 The Synapse as a Drug-Sensitive Biophysical Machine 8min
2 Nicotinic Acetylcholine Receptors: Activation 10min
3 Nicotinic Acetylcholine Receptors: Desensitization 5min
4 Inhibitory Ligand-gated channels 9min
5 Glutamate-gated receptor channels 11min
1 Pore Blockers at ligand-gated channels 6min
2 Voltage-gated channel blockers 11min
1 exercício prático
Quiz on Week 2 miniLectures32min
Semana
33 horas para concluir
Week 3. G protein pathways
The description goes here
10 vídeos (total de (Total 118 mín.) min), 1 teste
10 videos
2 Inhibitory G Proteins and their Effectors 7min
3 The Stimulatory G Protein (Gs) Pathway 11min
4 The Ca-mobilizing G protein (Gq) pathway; Modifying G protein Pathways 11min
5 “Outside-in” Mechanisms for Long-term Actions on G Protein Pathways 12min
1 Drugs Bind to Neurotransmitter Transporters 15min
2 Neurotransmitter Transporters as Molecules 11min
1 Overview 10min
2 Targets 8min
3 System level effects 14min
1 exercício prático
Quiz on Week 3 miniLectures38min
Semana
43 horas para concluir
Week 4. Nicotine Addiction
The description goes here
12 vídeos (total de (Total 145 mín.) min), 1 teste
12 videos
2 Circuit and cellular level. "Outside-In" Mechanisms 11min
3 Circuit and Cellular Level: Upregulation via “Inside-Out” Mechanisms 16min
4 Recent Genetic Data 13min
5 Drugs for smoking cessation; Harm Reduction 14min
1 Components of Opiate Addiction 10min
2 Circuits and Animal Models 10min
3 “Outside-In” Mechanisms 12min
4 Drugs for Harm Reduction in Opiate Addiction 5min
1 Clinical Description & Genetics 10min
2 Pathophysiology 16min
3 Biomarkers & Therapeutic Approaches 8min
1 exercício prático
Quiz on Week 4 miniLectures30min
Instrutores
Henry A. Lester, PhD
Bren ProfessorDivision of Biology and Biological Engineering
Sobre Caltech – Instituto de Tecnologia da CalifórniaCaltech - Instituto de Tecnologia da Califórnia
Caltech is a world-renowned science and engineering research and education institution, where extraordinary faculty and students seek answers to complex questions, discover new knowledge, lead innovation, and transform our future. Caltech's mission is to expand human knowledge and benefit society through research integrated with education. We investigate the most challenging, fundamental problems in science and technology in a singularly collegial, interdisciplinary atmosphere, while educating outstanding students to become creative members of society.
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