As an expert in infectious diseases, editor of the Journal of Infectious Diseases and author of the textbook Infectious Diseases: A clinical short course, McGraw-Hill April 2020, I have been concerned about the misinformation being shared about the COVID-19 epidemic. How did this disease develop? Where did it come from? How does it cause diseases? The answers to these questions will be answered in the first video of module 1. The world has been startled and frightened by the rapid spread of this virus throughout the world. In Video 2 the epidemiology as presently understood is reviewed. This video will be periodically updated recognizing the rapid progression of the pandemic. Many want to know how does this disease present, what are the symptoms associated with COVID-19? How dangerous is COVID-19? Who is at risk of dying? All these questions are answered in Video 3. And finally how is this disease best treated and how can we slow the spread of the infection? These questions are answered in video 4. In addition to the videos multiple choice questions are included to test your understanding and there is an epidemiology peer reviewed exercise designed to teach you how this infection is spread and to show the power of the tracing of cases and isolating those who are infected. The second peer review exercise will encourage you to create a campaign to shift your countries culture to embrace behaviors that can lead to suppression of the epidemic, behaviors that will save lives. After completing this course you will be armed with the knowledge and skills to make a difference and help to bend the curve.
oferecido por
COVID-19 - A clinical update
Universidade da FlóridaInformações sobre o curso
No background required.
O que você vai aprender
Understand how this coronavirus invades respiratory epithelial cells, grows in the nasal passages and spreads to alveoli to cause hypoxia.
Describe what makes this coronavirus so infectious, how it has spread quickly throughout the world and how best to stop its spread.
Recognize the clinical symptoms of COVID-19 disease and be able to diagnose this disease
List the recommended treatments for COVD-19, as well as the treatments under investigation
No background required.
oferecido por
Universidade da Flórida
The University of Florida (UF) is recognized nationally and internationally as a leader in academic excellence, both on campus and online. Ranked in the top 10 of Public Universities, the University of Florida is the state’s oldest university and has a long established tradition of academic excellence.
Programa - O que você aprenderá com este curso
How SARS-CoV-2 Causes Disease in Humans and Spread Around the World
Coronaviruses infect many species of animal including the bat. These RNA viruses frequently mutate particularly in bats, and chance mutations rendered the SARS-CoV-2 capable of readily infecting humans. The bat virus infected an intermediate host, possibly the Pangolin that was sold in the live fish and animal market in China. A key virulence (characteristic that allows a pathogen to cause disease) factor is the S protein which was the likely primary target of the mutations. This protein forms knobs on the outer surface of the virus that bind strongly to the ACE2 receptor on human respiratory epithelial cells. Binding is followed by internalization and within the cell the virus replicates its RNA using a replicase and assembles into a nuclear capsid in the host cell cytoplasm RNA is also translated into proteins that coat the outer surface of the virus. Once fully assembled the virus is exocytosed (released) from vesicles. The new viral particles can infect other cells and spread to other humans. The virus first replicates in the throat and nasal passages and then spreads to the trachea, bronchi and alveoli where it induces inflammation and damage to the alveolar walls causing fluid to leak into the air exchanging sacks and interfering with oxygen exchange. If inflammation continues the alveolar walls become fibrosed (scarred) and further compromising oxygen exchange resulting in decreases in oxygen saturation (hypoxia).
COVID-19 Symptoms and Signs, Diagnosis, Treatment and Prevention.
COVID-19 presents similarly to influenza. The most common symptoms are fever (>100.4 °F or 38°C), dry cough, and shortness of breath. Other common symptoms include marked fatigue, myalgias (muscle aches), headache, and sorethroat. Chest tightness can develop early in severe cases. Diarrhea and vomiting less commonly can be presenting complaints. Physical exam is usually unremarkable with the exception of fever, tachycardias (elevated pulse), an elevated respiratory rate and low oxygen saturation on room air. Lymphadenopathy is usually not present and pulmonary exam is unremarkable. Laboratory studies are nonspecific with a low lymphocyte count, low platelets, elevated CRP, and normal procalcitonin level. CXR is insensitive (60% sensitivity) chest CT being more sensitive and highly specific and is the study of choice in patients being considered for admission to the hospital.
Avaliações
Principais avaliações do COVID-19 - A CLINICAL UPDATE
Hellow I am samruddhi and glad to tell you that I had recive the good grades in this course and completed it. This course has taught me many new things and this is very helpful for my future.
I liked and appreciated the focus on public health issues and not just the medical and epidemiological factors of the disease. And excellent short course. Many thanks for preparing this.
A very informative course regarding the ongoing pandemic! Although it just needed some update due to recent data and studies. The instructor is great!
This course is really instructive and interesting.Very well designed and organized.It could be improved by giving more in-depth knowledge. Thankyou!
Perguntas Frequentes – FAQ
Quando terei acesso às palestras e às tarefas?
O acesso a palestras e tarefas depende do tipo de inscrição. Se você participar de um curso como ouvinte, você poderá ver quase todo o conteúdo do curso gratuitamente. Para acessar tarefas valendo nota e obter um Certificado, você precisará adquirir a experiência do Certificado, durante ou após a participação como ouvinte. Se você não vir a opção de participar como ouvinte:
- o curso pode não oferecer essa opção. Você pode experimentar um teste gratuito ou solicitar o auxílio financeiro.
- Em vez disso, o curso pode oferecer 'Curso completo, sem Certificado'. Com esta opção, é possível ver todo o conteúdo do curso, enviar as avaliações necessárias e obter uma nota final. Isso também significa que você não poderá comprar uma experiência de Certificado.
O que recebo ao adquirir o Certificado?
Quando você adquire o Certificado, ganha acesso a todo o material do curso, incluindo avaliações com nota atribuída. Após concluir o curso, seu Certificado eletrônico será adicionado à sua página de Participações e você poderá imprimi-lo ou adicioná-lo ao seu perfil no LinkedIn. Se quiser apenas ler e assistir o conteúdo do curso, você poderá frequentá-lo como ouvinte sem custo.
What is the refund policy?
Você poderá pedir reembolso total até duas semanas após a data do pagamento, ou (para cursos recém-iniciados) até duas semanas após o início da primeira sessão do curso, o que ocorrer por último. Você não poderá receber reembolso após obter o Certificado de Curso, mesmo que tenha completado o curso dentro do período de duas semanas. Veja nossa política para o reembolso total.
Is financial aid available?
Sim, a Coursera oferece auxílio financeiro aos alunos que não podem pagar a taxa. Faça a solicitação clicando no link Auxílio financeiro, abaixo do botão "Inscreva-se" à esquerda. Você será solicitado a preencher um formulário e será notificado se for aprovado. Saiba mais.
Mais dúvidas? Visite o Central de Ajuda ao Aprendiz.
