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Voltar para Comparação de genes, proteínas e genomas (Bioinformática III)

Comentários e feedback de alunos de Comparação de genes, proteínas e genomas (Bioinformática III) da instituição Universidade da Califórnia, San Diego

4.7
estrelas
126 classificações

Sobre o curso

Once we have sequenced genomes in the previous course, we would like to compare them to determine how species have evolved and what makes them different. In the first half of the course, we will compare two short biological sequences, such as genes (i.e., short sequences of DNA) or proteins. We will encounter a powerful algorithmic tool called dynamic programming that will help us determine the number of mutations that have separated the two genes/proteins. In the second half of the course, we will "zoom out" to compare entire genomes, where we see large scale mutations called genome rearrangements, seismic events that have heaved around large blocks of DNA over millions of years of evolution. Looking at the human and mouse genomes, we will ask ourselves: just as earthquakes are much more likely to occur along fault lines, are there locations in our genome that are "fragile" and more susceptible to be broken as part of genome rearrangements? We will see how combinatorial algorithms will help us answer this question. Finally, you will learn how to apply popular bioinformatics software tools to solve problems in sequence alignment, including BLAST....

Melhores avaliações

AH

18 de ago de 2016

A very well taught course that gives you the ins and outs of sequence comparision and introduces chromosme rearrangement analysis in a succint manner. This was

TF

24 de dez de 2016

Take your time, this course is harder than the others. Very worth it though, learned a lot and it was a lot of fun!

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1 — 25 de 25 Avaliações para o Comparação de genes, proteínas e genomas (Bioinformática III)

por ZIHAN X

9 de abr de 2019

por Christiane A

6 de ago de 2017

por Daniel D

24 de out de 2019

por Ricardo S

10 de nov de 2016

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2 de out de 2016

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7 de ago de 2022

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19 de out de 2017

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19 de mai de 2022

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25 de dez de 2016

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22 de jun de 2017

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20 de dez de 2021

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30 de nov de 2017

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26 de jul de 2020

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21 de jul de 2019

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24 de mai de 2018

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17 de set de 2016

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19 de jun de 2018

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13 de dez de 2016

por ­박준형 / 학 / 컴

12 de set de 2018

por José M P F

9 de ago de 2016

por Yudi,Tian

19 de mai de 2019

por Linbo Z

10 de jul de 2017